Esa means a Mexican homegirl.
Using esa is for females if u wanna call a homeboy its
ese.
However not all
homies use this.
Note that not all use this term.
Another term for esa would be homita which can also
mean lil homegirl using it for a male it would be homito.
some other Centro Americans use these terms as well.
But are mainly used by Mexican homies.