Oxy-codon. A prescription pill that comes im various sizes from 10-80 mg. It is usually used to help very serious back pain. It contains lab synthesized heroine and can be very addictive. A pill called subutex is available to help the addiction.

Yo lets get some cizzle tonight so we can rail em and have a good time
by DK 42 March 27, 2008
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Coricidin or DXM, in reference to the high frequency sound of one's brain frying after ingesting such chemicals, heard only by dogs.
That motherfucker ate a box of the cizzle and fucked a cat. Dude is seriously twisted.
by Mofockah July 4, 2007
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coke.. cocaine - a hell of a drug according to Rick James.
after smoking cocaine, me and sara got drips.
by Jizzle February 15, 2005
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Clarendon and parts of VA Sq, Arlington, VA; parts of zip codes 2201,2203. It is an urban neighborhood in north Arlington near the Clarendon Metro station. Comprised mostly of low-rises, this lies between the mid-rises of Ballston and Courthouse. It is home to a dense collection of bars and restaurants. The bulk of which are nigh best-in-area quality. “Cizzle-Dizzle” can be said, quickly, to the tune of the Metro door bell. Technically, "Cizzle-Dizzle" refers to Clarendon, but in practice it also can refer to its adjacent "neighborhood" Virginia Square, because it no longer exists. The Virginia Square neighborhood was named for the Virginia Square shopping center. However, in the summer 1988, the center was, more or less demolished, to make way for the FDIC building. Thus, Virginia Square is the neighborhood known as the formerly existing shopping center. In normal speaking, to avoid confusion, it's easier to just say "party in cizzle-dizzle""where?""VA sqr metro""cool". Functionally, “cizzle-dizzle” is the area within 2 blocks of the Orange Line between Oakland and Cleveland.
"You comin out tonight?""where you going?""Cizzle-Dizzle""word."
by Specificity January 23, 2012
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when you are going to get a hair cut so you look new and fresh.
by Deole December 10, 2006
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me:wuddop my crazzle?
friend:nuttin' much my nikka.
me:keepin' nit on dur realzes.
friend:fo' shizzle my cizzle.
by stephaniewakester February 16, 2004
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