Daryl: Did you hear about the Big Burger Merger that's going on?
John: No.
Daryl: Ronald McDonald stuck his Big Mac into Wendy's Hot 'n Juicy!
John: Sheeeeeeeeeeee-yiiiiiitttttt!!!!!!!!.
to fuck up; to be highly unsuccessful; to crash and burn in embarrassment with extremely unfortunate and dire consequences; to be defeated; a disastrous effort; to get royally beaten; to be demoralized and overcome by adversity similar to recent efforts by Quentin Tarantino to produce a good movie.
Dude, I knew she was gonna bite the big Kahuna Burger when she went out with your skank ass...all you wanted was a piece...she wanted to take you home to Ma and Pa