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Beeyou (pronounced "bee-yoo" or "byoo") is a sound effect turned adjective from the popular Nickelodeon "Nicktoon" Doug. Usually used to describe something terrible unfortunate or extremely distasteful, the pronunciation of the word varies depending on the effect one is going for.

The word is popular among Central Connecticut State University students, specifically those in EHBMTG.
Jes: So we found this girl passed out in the bathroom last night.
Rob: (laughing) Beeyou.

Or

Kelly: The alarm clock fell on Rich's head and ended up waking James up!
Dave: That's pretty Beeyou.
beeyou by Blackbirdxo January 23, 2008
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(verb, onomatopoeia): To toot one’s own horn. To boast, brag or draw attention to one’s own superiority. Origin: Mimicry of jazz trumpet sounds, scat singing.
Can be done both explicitly (e.g. blatant beenouing: “I am awesome at Ultimate.”) and implicitly (e.g. back-handed beenouing or fishing for compliments: “Have you seen me throw a Frisbee?”). Can also function as a noun (e.g. “This blog is a huge beenou.”). Also, a female beenouer is commonly known as a "feemou."
beenou by Poonology May 26, 2009
Related Words
Variation on bitch--as term of affection or as insult.
Who's the beeyotch now!
beeyotch by ian daffern March 12, 2003
The best way to make your sentence better.
Hey, I just won the lottery (beeyotch)
Beeyotch by Aces Rodriguez November 4, 2011
The state of feeling overbloated from having consumed too much beer. Can be partially cured by burping.
After four hours in the pub I felt incredibly beerous.
Beerous by dr ben August 12, 2012
"Beeyoo" (pronounced "bee-yoh") was a fad in 1940s United States popular culture, which mostly caught on due to the regular occurrences of it in Popeye and other propaganda cartoons. When it was said, it could vary from the short "beeyoo" to the longer "beeeeeeeeeeyooooooo", for comedic effect.
The fad died out in 1948, when it was dubbed a Communist exclamation by the American government. It was replaced by the more American "golly" ("goooooooooollyyyyy").
Goering: "Adolf? Shpeak to me!" *sobs*
Hitler: "Beeeeeeeeeeyooooooo!" (Beeyoo variant)

(1943 Popeye cartoon "Seein' Red, White 'n' Blue")
Beeyoo by Teeg Dougland April 28, 2007

beyounce 

Beyounce is very pretty like a goodess. She have a good heart. Can be annoying but she mean it of no harm . She is nice pretty and funny . She tries to find the best in people sometimes that don’t go right . But she finds friends just right for her eventually.
Hey beyounce .
beyounce by Beyoutothefullest February 10, 2018