Cory's blatant assholry was pissing his hard working friend off while he was trying to do his research paper. He wouldn't stop asking him annoying questions, and trying to pressure him into doing stuff he didn't want to do.
Describes the ability to tolerate people who think with their sphincter and share thoughts that are reminiscent of fecal coliforms. In other words, the greater your ability to spend time in the presence of an asshole, the greater your level of assholerance.
I can'tbelieve you let your in-laws stay for a week, you must have huge assholerance!