When someone comes to your house and farts all over the place. Even one fart can be considered assing it up.
That motherfucker done came to my crib and assed it up in my motherfuckin' heezy!
by Uncle Funkalunkel October 15, 2003
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The act of going over to someone's house and dropping some serious deuces. Can also be when you go to someone's house and rip a couple.
Damn, Mark is having a party. I'm gonna go to his house and ass it up in that motherfucker.
by Uncle Funkalunkel October 15, 2003
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Diahrea so explosive that it projects itself like vomit.
Dude that mexican food made my Ass Throw-up last night.

or

Who got Ass Throw-up all over the god damn toilette seat.
by jdice_bung1 April 29, 2009
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A method used to mask the identity of an embarassing booty call by comparing their looks to a celebrity.
Dude 1: "So what did that girl look like man! You slept with her and you're not giving me details!"
Dude 2: "Umm, she was ok... Kind of looked like Margaret Cho..."
Dude 1: "Dude, what the hell? Margaret Cho is not even fine, don't try that celebrity ass cover up on me doggy!"
by Da Vin Chee January 12, 2010
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(adj) The unsightly appearance of a person, place or thing. Commonly used in military setting when a superior scolds a junior (or group of juniors) for not keeping his/her/their appearance, living quarters, uniform, or equipment up to a standard of cleanliness and/or organization.

Synonyms: jacked up, fucked up, screwed up
Sergeant Slapstick: "Private Dingleberry!... I KNOW you did not just fall into my formation lookin so assed up... Get your stankin' ass back in the barracks to SHAVE, PUT ON A PRESSED UNIFORM and CLEAN YOUR BOOTS, you fuckin' fuckstick!"

Drill Sergeant Payne: "WAKE UP, 1st PLATOON!!! Now I KNOW y'all didn't go to bed last night leaving my bay floor lookin' so assed up! TOE THE LINE!!!"
by Bozo McScrotus June 2, 2016
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To create a complete mess; establish a state of disorder akin to immersing oneself in a world of unpleasant ass.
Don't do it, man. Adding that coconut milk would seriously ass up the marinara sauce.

OR: The project was moving along smoothly until Jared completely assed everything up.
by speedgoat January 17, 2008
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Asses up is a game played in parks, schoolyards or anywhere kids can find a large flat wall to throw a ball against, like the one in Buchmuller Park in Secaucus. The ball of choice is a sponge ball or “spongie,” or even a tennis ball. Basically, you have 2 or more kids throwing the ball against the wall and each person has to catch the ball. If you drop the ball 1 or more times (depending on the rules established), you have to put your ass up against the wall to be beaned by each other person playing the game. Sometimes, the guy throwing the ball can call out someone’s name and that person has to be the one to catch the ball. If you fail to catch the ball, ASSES UP! The game is a lot more fun if you play with fat kids who aren’t quick enough to catch the ball. Plus, their butts make great targets.
Kid 1: We are going down to Buchmuller Park to play Asses Up, are you in?

Kid 2: Be nice when throwing the ball at my butt, Dr. DeAngelis just gave me a shot of penicillin.
by shredder666 August 16, 2011
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