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In no-limit poker, to bet all of your chips as a sign of total confidence in your hand.

If you have a very good hand, go all-in to win the maximum number of chips or to scare off mediocre hands so they won't catch the cards they need to beat yours. If you have a bad hand, you can bluff by going all-in and hope everyone folds.
I went all-in on thirty miles and that river rat caught a runner-runner flush.
all-in by Coell December 28, 2005
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A donkey's favorite action in poker. When used by a shark it means the odds are in his favor so fold or possibly that he is willing to gamble for the pot, are you?
The donkey went all-in for the fifth time in a row.
all-in by AlienSorrow June 16, 2007
To be totally committed to something.

Possibly originating with gambling games such as Texas Hold 'em style poker, where the maximum 'raise' is to bet your full stack of chips.
If we're gonna do it, let's do it. I'm all in.
all in by Honor June 23, 2004
When you place all your eggs in one basket.
Jim: Yo John, how much money are you going to put in that stock
John: Hey buddy, I'm going all in by selling my wife, house, car and kids
Jim: Cool
all in by John Kennington February 8, 2021
To enter all of your poker chips on one hand.
When he saw he had a royal flush, Muhammed Ali went all in.
1. Investing all of your holdings at once, as in a single hand of poker.
2. Extremely tired, or at wit's end. (slightly archaic)
1. You went all in on a pair of nines?
2. I can't talk about this right now, I'm all in.
all in by mycrows March 8, 2010
When not used in a poker game context, "all in" means that one thing is completely inside something else. No more of said object will be able to enter after this point. Often used in sexual situations.
Linda Tripp: "Go deeper baby, I can't even feel it."
Gary Coleman: "I can't, bitch...I'm all in."
all in by Nick D July 28, 2004