Urban Dictionary: on one

Top definition

Just generally trippin', tweakin', weird, actin' a fool, blackin' out, goin' off. Not necessarily due to drugs, though that's the obvious reference.

Homie was on one, just buggin' like I shot his mom or something.

by Kuahmel January 22, 2009

May 11 Word of the Day

A euphemism for “kill me” now that composting oneself after one’s death has become popular.

All right, why don’t you just compost me?

by Dr Bunnygirl March 22, 2020

To be fucked up on whatever your drug of choice is. It is beyond just tipsy or lightheaded, it's full on faded/twisted/tweaked/trippin/high/etc.

Damn, Rick James was on one back in the 80's.

That bum jackin off in the corner must be on one, damn tweak.

by Joe Blaze January 25, 2008

to be under the influence of methamphetamines

i heard joe's been on one for the past three days

by Leya Fish January 19, 2003

Slang used to describe when someone is in a bad mood

"Man, I dont know what Susans problem is but she's On one!"
"Yea she's been a crank lately"

by Aschattack June 02, 2018

To be under the influence of methamphetamines AKA ice,meth,speed,dope,etc.

Tuttie's on one man, he been smokin' ice all week!

by rooster760 February 28, 2005

Just broke up with my girl and this alone time has me feelin' on one right now.

by Fresh Livin' May 05, 2015