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To have smarts/be smart, but usually not in a knowing calculus at the age of 6 smart, but just being aware and making smart choices. Mostly known for "Keep your wits about you." quote from several films,games and media that date back in the days(medieval etc). Meaning just keep your head up and be smart about what you do, be careful.
Malik decided to get piss drunk right before finals and didn't even study, he failed the test the next day, he sure as hell didn't keep his wits about him.

Take this sharp stick, it's all I have to give you before you venture off onto your jourey... but with just a stick, be sure to keep your wits about you, Sir Mark.
Wits by Zure the Dark Being April 16, 2013
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Wits means “What is this shit?” So when you show a video to your friends and they say “Wits?”it means What is this shit.
Person: “Hey man! Look at this video 😂”

Freind: WITS???
Wits by Yasthequeenshaissa May 16, 2022
Related Words
What is this shit? Used liberally in the military for staff work that is poor in quality or annoying from another person.
I sent the Captain the report from the IG and he scrawled "WITS" all over the front
wits by entropy666 January 18, 2008

Wits University 

Wits university is the University of witswatersrand situated in the city of Johannesburg south africa. The university is populated by people who think they are in Harvard meanwhile they're one of the most dumbest people ever. Most of the girls sell their bodies to Nigerian drug dealers in order to pay fees and the boys are Mongols. The whole university should be divided by 2 because they are all halfwits.
Person A: I Got Admitted at Wits University.
Person B: "Congratulations you're a prostitute: (If Person A is female)
else
(Congratulations you're a nyaope boy).
Wits University by Thedarklol July 26, 2022

wits mind 

You are very smart!
(Used when you think someone is smarter than you, or somebody else)
Teacher:what is 4+6? Um Layla

Layla: I don't know
Teacher: candela do you know?
Candela: 10

Other Student: good job candela you have wits mind!
wits mind by Melodicvoice August 19, 2017

keep your wits about you 

To keep your mind in focus, to not let your guard down no matter what.

To think carefully before an action, regarding the consequences that may be dangerous for you and/or others.

To stay sharp!
Alex: I'm going on holiday to London, should be awesome!

Jess: There are loads of grifters and cons, so keep your wits about you and stay out of trouble.

sneaky be's wits 

Hooking up with someone that you don't want anyone to find out about. Sneaking around to to be with someone.
Are you trying to get some sneaky be's wits from that girl?
sneaky be's wits by fatbox November 28, 2005