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A latino street gang named after 26th ST in Chicago's Little Village community. The gang was originally a neighboorhood baseball team called the Two Sixers but formed as a street gang in the 1960's. One of Two six's biggest rivals is the Latin Kings.
Hey ese, look at that vato walkin down 26th, he wearin' black & tan, he must be a Two Six.
A slang term for b.o. otherwise known as body odour. The numbers stand for the letters, they way they appear on a telephone keypad.
"The guy next to me ordering a drink had the worst two six."
two six by KJ March 1, 2005
A Canadian term for a 26-ounce bottle of alcohol. The modern bottle is actually 750 mL (25.36 oz), but it is still commonly called a two-six nonetheless. (See also: two-four.)
I finished off a two-six of rum in one evening, and did not feel good the next morning.
That cheap-ass didn't tip again! He's always two-sixing me!
two-six by White Kiwi July 1, 2008
Year 2026 is here lets bring back

"Two-six" (or 2-6) is Canadian slang for a standard 750ml bottle of hard liquor, originating from the old 26-ounce imperial measure of liquor bottles before metrication, surviving as a popular, shortened term for that size, similar to a "fifth" in the U.S.. It's a key piece of Canadian drinking culture, alongside "two-four" (a case of 24 beers) and "Mickey" (a small bottle).

Origin: Came from the 26-ounce capacity of pre-metric liquor bottles in Canada, notes the Dictionary of Canadianisms on Historical Principles (DCHP-3).
Metric Shift: The term stuck even after bottles switched to 750ml (about 25.4 oz) in the 1970s/80s, according to the DCHP-2.
Usage: You'd ask for a "two-six of rum" or "grab a two-six" for a party.
Canadian Slang: It's a distinctively Canadian term, alongside other sizes like a "Mickey" (375ml) or "Texas Mickey" (3L).
"Before the party, we have to stop at the LCBO to pick up a two-six of vodka".
Two-Six by Youdoodoo December 31, 2025

Gangster Two Six Nation 

He got shot by the gangster two six nation
Gangster Two Six Nation by Fidndndd February 19, 2018