Spidoof Share definition Flag A word to be said after smacking an aquaintence or perfect stranger on the top of the head with a large book or the back of the hand. -Hey Joe -Yeah (confused) *whack* -SPIDOOF!! Spidoof by Jamie Parker September 21, 2005 0 0 Get merch Get the Spidoof mug. Buy Now — $32.95 See more merch