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Sibstitution

The practice of substituting one's friends for their own genetic siblings. May be due to geographic or emotional separation. Sometimes this practice is colloquialized as a brother from another mother BFAM.
Steve's brother couldn't make it to the game, so he made a last minute sibstitution with his friend Mike. Stacy sibstituted her friend Becca, because her sister lived 12 hours away.
Sibstitution by BiochemDude June 14, 2016
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ligand substitution 

The act of replacing a ligand in a complex ion. This results in a change of colour of the complex ionic solution.
Rasta: What does ligand substitution do?
Me: Ligand substitution results in a different coloured solution!
ligand substitution by TheWizoid November 13, 2016

A "Greg Scott" Substitution 

Whilst playing Fifa online, pretending to make a substitution then quitting due to being one or more goals behind.
I was beating him 1-0 with 5 minutes left to go and he made "A "Greg Scott" Substitution"

substitution 

5 foot Jen is paying for her college through substitution.
substitution by Lori-Ann January 29, 2008

Suxstitution 

To replace something that is just "OK" with something far worse.
This crappy rental car is a suxstitution for my corvette while it is the shop.
Suxstitution by t-boy May 27, 2012

pillow substitution 

The act of switching pillow faces when a pillow becomes too warm due to absorption of the sleeper's body heat. This act can be accomplished by turning the pillow over, revealing the unused and cool side, or by getting a new pillow.
Last night I was pretty hot after doing my girlfriend. So my pillow got really hot and I couldn't fall asleep. That's when I pulled a pillow substitution. It was some tag-team, fresh action.
pillow substitution by juanch June 17, 2010

substitution property 

The idea that if a = b, then a may be replaced by b in any mathematical or algebraic expression.
If x = 3, then use 3 instead, its part of the substitution property.