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osteoporosis 

A bone disease which makes bones brittle. Mostly said because iDubbbz said it once and it sounded amusing, hence it became a meme.
"I have osteoporosis!"
osteoporosis by Shark Lover October 10, 2017

Testicular Osteoporosis 

Whenever your balls are drained and there’s no more cum
Yeah I beat my meat too much so now I have Testicular Osteoporosis

Osteopelosi 

The state of near facial paralysis resulting from an addiction to plastic surgery. Eventually, its victims begin to appear as if they are being anally raped, 24 hours a day, 7 days a week. (See also: paralystallone, kennyrogeritis, almichaelangelo.)
Franco Genovese: "Wow. Is it just me or is Joan Rivers starting to look more like Mickey Rourke than...well...Mickey Rourke?"
Malibu Jackson: "She's got Osteopelosi. I find that very sad."
Franco Genovese: "Yeah. So does Mickey Rourke."
Osteopelosi by Genovese, Franco January 8, 2012

osteoporosis 

One of the most seductive words to say to a girl.
I have osteoporosis.
osteoporosis by Manuele Pepe November 11, 2017

osteoporosis 

A infamous meme. It is actually a disease where bones lose mass and become weak and brittle.
AGGH!! Im falling apart! I must have osteoporosis!
osteoporosis by Fearborne November 24, 2018

osteopornosis 

A diagnosis of when a man has jerked his dick so much that his arm has adopted to a position of ease to no longer provide stress on the forearm. Also when one forearm is extremely larger than the other.
Damn man, I thought Jerry been wearing the wrist brace cause he had carpal tunnel surgery, Hell come to find out he just had a bad case of osteopornosis.
osteopornosis by picmeup March 2, 2009