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The couple name given to Grey's Anatomy characters Meredith Grey and Derek Shepherd. It's only used outside of the show, when fans are talking about them.
Did you see last night's episode of Grey's? You see that McDreamy moment? I love merder!
Merder by Maybelle29 July 3, 2009
The couple name given to the Grey’s Anatomy characters Meredith Grey and Derek Cristopher Shepherd. They are the iconic couple of Grey’s. They can make you feel sad, happy, depressed and other emotions. They are really everything for every Grey’s Anatomy fan. They have the perfect chermistry with all the best ingredients for the perfect couple so if you don’t watch Grey’s Anatomy you should start it now just for those two soulmates
Derek was epic for her, they were the great love story. I mean it never occurred to me that she would be with everyone else, he was perfect, he was everything, the man that turned her world, merder forever.”
Merder by Maguireswife April 21, 2018
a type of insane muderer who kills with a meathook or a wooden pole
john is a merderic and will be sent to a insane new home
merder by kingofsin666 April 1, 2007

merderlize 

totaly mess up some ones face body then the dead body
kill them twice before they hit the ground

im going to merderlize aklesh

goldberg VS YOU
merderlize by evil & MaZ May 8, 2004

merdersexual

when you feel a special connection to Meredith Grey and Derek Shepherd as a couple. you would do anything to make them have a happy ending.
me: i’m a merdersexual
someone: what is that?
me: i’m in love with merder from grey’s anatomy and i hope them to be an endgame
merdersexual by merderendgame April 25, 2021

void.merder 

A amzing bitch who likes bed her friend/son @void.wesleyy she loves Vanessa Morgan and would like to fuck her she is very nice and saskia is a very lovable person
Person 1:hey did you watch void.merder live person 2:who tf is void.merder person 1:a very nice person :))))))(
void.merder by Void.wesleyy January 10, 2019