To obliterate, destroy, or kill something, usually a living being, using excessive violence and/or force.
Another way to describe murderizing something would be overkill.
It is not used often, and even when it is used it is often ridiculous and non serious
Katelyn murderized the cockroaches with her flamethrower
Alex murderized his friend with a dull knife for his satanic ritual.
After being infuriated by her neighbor's actions, Natalie murderized the entire city with nuclear weapons.
Nickname given to bales of marijuana thrown overboard or out of airplanes. Origin is reportedly from members of the US Coast Guard in the area of Southern Florida.
"Base we've got some square groupers floating outside of Miami harbor."