When Someone Doesn't have their medication making them hyper; When Someone has no Ya yo and starts to get psycho; When someone turns unbeleivably gay.
by creammm January 19, 2005
Get the Mattitismug. A word made up by two spontaneous girls dalanee and brooklyana and is a nick name for mattia polibio
by Stupidpersonwhowillneverbefamo October 26, 2020
Get the Mattitiemug.