A time when a man's chemical balance becomes shifted and he has a breakdown and/or becomes an asshole. Symptoms include- Irritability, mood swings, thoughts of suicide, depression, over sensitivity, paranoia, and feelings of helplessness.
When Mike turned 50, his manopause kicked in and he bought a Corvette and then drove it off a cliff.
A serious condition where someone’s feet makes a noise that sounds as if they slathered mayonnaise in-between their toes and smack their feet on the ground while they run.
Gonzo: Patrick has some serious mayonnaise feet. I can hear his toes smacking the stairs.
Geffy: Yeah, the poor guy was diagnosed last year.