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Refers to Manhattan's "LOWER EAST SIDE"- A neighborhood in lower Manhattan that is overridden with hipsters, yupsters, and trustafarians. What used to be a somewhat dangerous and sketchy area of Manhattan is now being gentrified by white kids.

This area requires a ridiculous amount of rent for a shitty apartment. The yupsters prefer living in The Blue and other high rise condos.

If you live here, Ludlow is your main street, Whole Foods on Bowery is your grocery store, and you have beef with the hipsterkids in Williamsburg- unless you are dating one, which since a bridge is involved, is considered a "Long Distance Relationship" anyway, so you don't have to worry about hooking up with some one at Happy Endings or whatever the next MisShapes DJ set is.
Hipster: Yeah, I'm gonna stay around the L.E.S tonight- probably hit up the Darkroom, maybe check out The Annex, my friend's band is playing there.

Yuppie: I'm going to head down to the L.E.S this weekend and get some sweet hipster ass.
L.E.S by hipper than thou August 19, 2008
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L.E.S stands for Lady Eric Security it is the most sophisticated security company in the world, where the Head Quarters are located in Canada.
Sir we need L.E.S to take care of this issue.
L.E.S by Securimaxx June 9, 2010
Related Words
Low End Syndrome

Symptoms include - lack of experience, foresight, common sense and poor decision making.
Guy 1

I can’t believe he would make such a poor decision, clearly he lacks knowledge and experience.

Guy 2

I was told he was diagnosed with L.E.S couple years back.
L.E.S by DillyDylan April 13, 2014
Live Every Second. It is a motto slightly similar to YOLO. Carpe Diem!
Hipster: YOLO!

Me: That's old school! L.E.S.!
L.E.S. by ToneD February 16, 2013

L.E.S.B.I.A.N.S. 

(N.) an acronym for the Large Experimental Super Busty International Amazon Nuclear Squad. (think of a sci-fi version of Xena) Four women from the U.S. , England, France, and Germany get zapped by nuclear radiation and gain superpowers. Set to air on NBC in Fall 2003. Anne Heche set to guest star.
Hey, guess what I just did today? I just totally checked out some L.E.S.B.I.A.N.S.!
L.E.S.B.I.A.N.S. by G-Union May 19, 2003

É.C.O.L.E.S

French word for school

Endroit
Cruel
Òu
Les
Élèves
Souffrent
J’ai vraiment pas le goût d’aller à l’É.C.O.L.E.S aujourd’hui
É.C.O.L.E.S by Al_ex.lec June 11, 2019

A P P L E S A U C E 

Person A : Hey I got an A+
Person B : A P P L E S A U C E
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