1) Monty Python: A hand grenade forged to smite the powers of evil. Instructions: Pull pin, count to three, throw.

2) Worms: MOST POWERFUL WEAPON EVER. Or at least the coolest. A parody of the Monty Python weapon, the holy hand grenade is an awesome weapon which shouldn't be reckoned with.
1)And Saint Attila raised the hand grenade up on high,
saying, 'Oh, Lord, bless this thy hand grenade that with it thou
mayest blow thy enemies to tiny bits, in thy mercy.' And the Lord
did grin, and people did feast upon the lambs, and sloths, and
carp, and anchovies, and orangutans, and breakfast cereals, and
fruit bats, and large...

2) wURmz_Masta: i totly pwned u wit tht holy hand grenade. haha
by Lyrax February 26, 2005
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The preferred weapon of God, set to exploded after 3 seconds (not 4, nor 2, 5 is way out), and always kills the target.
by Extreme June 19, 2004
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First you pour diet coke in a girls vagina. Then you grab a handful of mentos and fist fuck her for a count of three. Do not count to four, nor two, lest it proceedeth you to three. Five is right out. Then get the hell out of the way.
"The other day I was fisting my girl and she said 'hey, let's try something kinky' so I gave her the Holy Hand Grenade. I was cleaning diet coke off of my walls for three days.
by BizarroTravis May 14, 2009
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After finishing in a condom you hold the base and pee into the the condom creating a water balloon, you then pop the condom on her face.
After I finished fucking her I dropped the Holy Hand grenade on her face.
by HlyHndGren October 16, 2019
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Peeing, Pooping, Cumming, Sneezing, Coughing, and Puking all at the same time.
Bro why is he running so fast? Hes about to do The Holy Hand Grenade
Charlie you look like shit? "Yeah, I just had to do The Holy Hand Grenade"
by LovelyBritz February 24, 2019
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Codenamed: "rabbit killa'" A device of mass destruction engineered and developed by monty python.
Thou shelt lob thy Holy Hand Grenade at the foe, only after the count of 3.
by mad at the world February 28, 2003
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A Reading from the Book of Armaments, Chapter 4, Verses 16 to 20:

Then did he raise on high the Holy Hand Grenade of Antioch, saying, "Bless this, O Lord, that with it thou mayst blow thine enemies to tiny bits, in thy mercy." And the people did rejoice and did feast upon the lambs and toads and tree-sloths and fruit-bats and orangutans and breakfast cereals ... Now did the Lord say, "First thou pullest the Holy Pin. Then thou must count to three. Three shall be the number of the counting and the number of the counting shall be three. Four shalt thou not count, neither shalt thou count two, excepting that thou then proceedeth to three. Five is right out. Once the number three, being the number of the counting, be reached, then lobbest thou the Holy Hand Grenade in the direction of thine foe, who, being naughty in my sight, shall snuff it."
King Arthur: Right. One... two... five.
Galahad: Three, sir.
King Arthur: Three.
by dip July 20, 2004
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