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Fussyhole 

A typical insult, generally used in disbelief at someones actions, behaviour or overall personality - think Paul Danan from Celebrity Love whatever!

No real origin other than that person is (or is being) a "fussy hole".

Can be used generically to insult people like words such as muppet, twat or dickhead, with the bonus that its not a bona-fide swearword so can be used almost anywhere at anytime.
"You're such a fussyhole!!!"

"Don't be a fussyhole"

"Paul Danan, he's a fuckin' fussyhole that boy"
Fussyhole by Jimbob101 August 3, 2005
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Fasshole 

A combination of the words "fat" and "asshole"
Most often used when describing an offense made by an overweight person.
"Hey! That fasshole totally just cut me off!"
Fasshole by cinderelmo December 23, 2005

fassyhole 

Probably the most offensive term in the Jamaican lexicon, fassy essentially means crusty or infected, with hole meaning vagina. WARNING: Saying this to a Jamaican will result in serious injury and/or death
Si dem gwaan a door? Dem look like fassyhole to I an I. (Trans: See those gentlemen exiting the establishment over there? I do believe they seem to have a striking resemblence to a crusty vagina!)
fassyhole by Dan Durell August 8, 2003

pussyhole 

a guy who does not behave like a man.
back of yuh raasclat pussyhole or mi a go bloodclat kill yuh!
pussyhole by pussyfinder July 25, 2003

pussyhole 

A slang commonly used in Jamaica generally for backstabbers or guys how gets rich and switch. Otherwise, it is an all purpose insult.
eg. That pussyhole did not remember to pick me up last night
pussyhole by punsy April 3, 2007

Pussyhole 

A Jarod that complains all the time and bitches like a woman.
He ran his mouth like a pussyhole because he was early to the job.
Pussyhole by Uadouche January 25, 2019

Fassyhole 

A highly offensive term in Jamaican Patois that is directed at a person who is strongly disliked. It is derived from the word "fassy" which means "sore" or "infected".
Keisha - "Move out mi way, bitch"

Mitsy - "Fassyhole! A who yuh talk to like that?"
Fassyhole by MTBamba August 18, 2018