Something that is visually displeasing. Can be a messed up pattern, vibrantly colored object that doesn't belong, or anything that just looks annoying.
basically let's just say...oh I don't know....not a pretty titty. A sight to see. Yet iconically leaves you with a feeling that you wished you hadn't. Cross eyed rack. One of pancake sized nipple goes southwest & the other northeast. Whoa!
ralph: Do you know what a spiritual eyesore is?
ned: Do I? Shit! I'm married to one, buddy. Hello?
fiona: Hey! I heard that, motherfucker!
ned: Oops! Sorry, dear!
Eyesex is when you get a girl to takeout her glass eye before sex entry, but eyesore of eyesex is the black and blue around the eyes and nose from my balls banging on her face.