It's a line from the 1987 film RoboCop. Spoken by an executive of a weapons manufacturer immediately following the death of his colleague at a failed demo of their new mechanized law enforcement robot. The character exemplifies the callous, dog-eat-dog mentality popular amongst business execs in the 80’s. It borders on sociopathic — similar to the nature in which Patrick Bateman speaks in American Psycho.
Cox: Too bad about Kinney, huh?
(Kinney shot to death by mech minutes ago)
Morton: *shrug* That's life in the big city.
The meaning of life is not something the human brain is capable of understanding. It’s like an ant trying to understand the Wall Street Journal. We’re not supposed to know the meaning of life. That’s the cruel hoax on mankind. Don’t even try, be happy in your ignorance.