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whatsisface 

when u forget someones name and you say this with a descriptive explaining who they are hopefully getting acknowledgment or a name
i know who scarfed down your burrito it was whatsisface who smells like yeast
whatsisface by DUGZSANTA January 9, 2005

Whatisitis 

A life threatening disease that can be contracted through excessive existential questioning. Some symptoms may include depression, substance abuse, social withdrawal, identity crisis, and a shitload of other dysfunctions. Although deadly, this disease can be cured with a large dose of distraction, available in both physical and mental forms.

Please note that even after a person has recovered from Whatisitis, it will never leave the body of the carrier. It is, however, non-hereditary. You can also attempt to spare your children the uncertainty of life by introducing them to extra-curricular activities and/or by brainwashing them.
You: What is that? *squinting*
Me: What is what?
You: What is THAT? *points to object in distance*
Me: What is WHAT? *using air quotes*
You: No, I'm serious.
Me: What is serious?
You: Ugh.
Me: What is ugh?
You: *thinks harder* Holy shit my brain is on fire... stop.
Me: What is stop?
You: *catching on now* What is is?
Me: What is what?
You: What is what is?
Me: Damn, I don't know what anything is anymore.
You: Me neither.
Me: Sorry for giving you Whatisitis. Then again, why am I speaking? Nothing makes sense! What is speaking and what is sense?!
You: Wanna smoke up?
Me: What does that mean? Oh fuck it, where's my bong?
Whatisitis by strawberryweedles April 12, 2010

whatishotspot25 

best roblox player beat eggamental 999999999999999999999999999999999-0
robert:whatishotspot25 fucked my mom builderman: he fucked my mom too.

whosee whatzits 

When some forgets what the thing they are talking about is called. Usually used by grandmas and clueless friends// see thingamabob
Hey, will you pass me those whosee whatzits?

Whatisit 

A game invented in the early 21st Century by someone in Suffolk, UK on facebook.
A close up of an object is posted on the individual's facebook with the tag Whatisit?

Once you have made an attempt at an answer - your inbox will be full of other peoples guesses in minutes...
Isn't Whatisit? frustratungly facebooky?
Whatisit by astralandrew April 8, 2011

whatzimagigie 

it is a thing when you dont know how to call something by its name you can say whatzimagigie
its a,a,a whatzimagigie
whatzimagigie by Calamity Jane January 24, 2006