Whatisitis 

A life threatening disease that can be contracted through excessive existential questioning. Some symptoms may include depression, substance abuse, social withdrawal, identity crisis, and a shitload of other dysfunctions. Although deadly, this disease can be cured with a large dose of distraction, available in both physical and mental forms.

Please note that even after a person has recovered from Whatisitis, it will never leave the body of the carrier. It is, however, non-hereditary. You can also attempt to spare your children the uncertainty of life by introducing them to extra-curricular activities and/or by brainwashing them.

You: What is that? *squinting*
Me: What is what?
You: What is THAT? *points to object in distance*
Me: What is WHAT? *using air quotes*
You: No, I'm serious.
Me: What is serious?
You: Ugh.
Me: What is ugh?
You: *thinks harder* Holy shit my brain is on fire... stop.
Me: What is stop?
You: *catching on now* What is is?
Me: What is what?
You: What is what is?
Me: Damn, I don't know what anything is anymore.
You: Me neither.
Me: Sorry for giving you Whatisitis. Then again, why am I speaking? Nothing makes sense! What is speaking and what is sense?!
You: Wanna smoke up?
Me: What does that mean? Oh fuck it, where's my bong?

Whatisitis by strawberryweedles April 12, 2010

Whatisit 

A game invented in the early 21st Century by someone in Suffolk, UK on facebook.
A close up of an object is posted on the individual's facebook with the tag Whatisit?

Once you have made an attempt at an answer - your inbox will be full of other peoples guesses in minutes...

Isn't Whatisit? frustratungly facebooky?

Whatisit by astralandrew April 8, 2011

Whitilitis 

Paranoia, anxiety that many white people feel after smoking pot.

That joint gave you whitilitis?

Whitilitis by Whiteisright January 20, 2009

whatisthisness 

It should just kinda explain itself...

Francisco: whatisthisness
Salvador: idk what’s going on either

whatisthisness by Thetruthhteller11 April 1, 2019

whoisitis 

A disease caused by whos

I can't be around who's or I'll get whoisitis

whoisitis by Mason Robertson May 2, 2017

whatsitsface

very odd way of saying "who is that?"

remember that guy from the store, whatsitsface

whatsitsface by anonymous October 18, 2020