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It's short for "Ta-ta-for-now" like when Tigger from Winnie The Pooh says it because he does not like to say goodbye.
Tigger:*Bounces on tail* "Well it's not goodbye instead it's T.T.F.N... ta-ta-for-now!!!"
T.T.F.N by AngieBlohm October 21, 2017
Talking For Nothing

When a bitch just running his or her mouth for no apparent reason
Girl: What is she even talking about?

Girl's Friend: I don't know girl she's just T.F.N.
T.F.N. by MelodyRoxxx February 28, 2015

THE TF NATION 

The tF nation is the most proest group of Gamers the world will ever see. Also known as the TFGA(Testicular Fortitude Gamer Army) we send out chaos to all who oppose us the TFGA plays Counterstrike source WoW and Battle Field 2(not as much as the others). All who challenge us fall even those who havent challenged us yet!!!
Gamer1: OMG ITS THE TF NATION RUN FOR YOUR LIVES!!!!!!!!
Gamer2: OMG DONT PWNT ME!!!
n33b: Lol Time to Pwn some noobs eh?
Bumblebee: Damn straight lets kick some ASS!!!!

A.T.F.N. 

“Yo man you wanna go to the party tonight?”
“A.T.F.N.”
A.T.F.N. by Allisun:3 May 31, 2018

T.I.F.R.Y.B.F.W.N.S.F.B.W.Y.T.M.O.T.M.F.S.W.Y.T.D.W.R.A.B.F.B.O.L.B.A.I.C.U.T.A.I.G.B.T.F.O.Y.B 

This is for Rachel you big fat white nasty smelling fat bitch why you took me off the motherfucking schedule with your trifflin dirty white racist ass you big fat oompa loompa ass bitch i’m coming up there and i’m going to beat the fuck out of you bitch
Karen: Where is your manager?
Manager: T.I.F.R.Y.B.F.W.N.S.F.B.W.Y.T.M.O.T.M.F.S.W.Y.T.D.W.R.A.B.F.B.O.L.B.A.I.C.U.T.A.I.G.B.T.F.O.Y.B

D.T.F.A.N.D. 

Friend 1: “how do I explain that I just want dick from him and not a relationship
Friend 2: “D.T.F.A.N.D.”
D.T.F.A.N.D. by Shartlett November 17, 2022