sis-sis

A best friend that you can call sis-sis instead of sis. Female version of brobro. Guys can have a best friend that is a girl that you can call sis-sis and nothing is going on or no one is going out.. Normally if you are best friends you can treat her like a real sister. You can love her like a real sister say I love you like you say to a real sister. Basically best friends.

Jason: Wow Chelsea, we have been friends for years now and I proud to call you my sis-sis.

Chelsea: Thanks Jason! Can I call you brobro?

Jason: Sure sis-sis.

Chelsea: Love ya brobro.

Jason: Love ya sis-sis.

sis-sis by Thekidwhoisakidthatgoestomps January 25, 2011

IUD SIS / SIS IUD 

This is an acronym from the Peaches Song "Fuck the Pain Away." While "SIS" probably does stand for "Stay In School" "IUD" does NOT stand for "Injustice Under Dog" as stated in the other listing for this pair of acronyms. It stands for "Intra-Uterine Device," a free form of birth control provided by Planned Parenthood. Peaches is encouraging girls to stay in school by not getting pregnant.

"IUD SIS / SIS IUD... stay in school cause it's the best."

IUD SIS / SIS IUD by morebettermostrighter January 9, 2010

IUD SIS or SIS IUD 

In the Song "F*ck the pain away" by Peaches one of the lyrics is IUD SIS then later she mentions to stay in school
the acronym siply means "Stay in School, Injustice Under Dog"

"IUD SIS, Stay in school 'Cause it's the best."
simply Backwards SIS IUD

IUD SIS or SIS IUD

IUD SIS or SIS IUD by Coco Loco Croco February 19, 2009

hoh sis 

hoh sis is a name repeated throughout YouTube poops made by YouTuber cs188 usually mentioned along with the joj

You want the JOJ right? And you want it even more that the first time? Then why don’t you call hoh sis

hoh sis by James McCree October 1, 2018

good sis 

A best friend, someone loyal, someone you love

I had to go the volleyball game to support my good sis.

good sis by lightbrightaduh May 4, 2018

Fuck it up sis 

something you say to hype up your pal.

My friend Daquania looked hot so I said “fuck it up sis”

Fuck it up sis by dickslayer6969 December 26, 2017

step-sis 

a horny bitch who is constantly getting stuck under the bed

step-sis: help me im stuck
bro walks in room
step-sis:what are you doing step bro????

step-sis by 6969696969696ix9ine March 12, 2020