sis

Short for sister, commonly used as a term of endearment to friends in urban new york/jersey areas
by Caroline Might Fine November 14, 2016
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sis

Not meaning “sister”. Commonly used to refer to a close friend or bestfriend.
what’s up, sis”
by kaitlyn pender January 24, 2019
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sis

1) Short for sister
2) In the song Fuck the Pain Away by Peaches, SIS seems to stand for Stay In School...
My sis went to the movies with a scumball.

"Stay in school... Cause it's the best..."
by wxynot July 31, 2005
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sis

by Thunderchild March 25, 2003
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sis

the abbreviation of "sister";
a genderless term much like "bro" or "dude"

people can also say it like "sister" but that doesn't change the definition

like when you say "brother" instead of "bro"
-"How do you feel about celebrity drama?"
-"It's the tea, sis."

-"Hey sisters!" -James Charles

-"How u doing?"
-"I'm so fucking depressed, sister"
by Bakuhoe Katsubitch January 09, 2019
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sis

1.) A South African English expression roughly equivalent to the American "yech" and the Afrikaans expression "sies".

2.) An American term of endearment for a sister, now also used in other countries.
1.) Sis, man, you stink!

2.) Hey, sis, hey bro, how's Ma doin'?
by Xaviana December 01, 2003
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sis

by emolay;) June 13, 2018
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