While the phrase may give the impression that the speaker is, possibly, suicidal; this is not actually the case.
One uses this phrase to express ones extreme displeasure with a given situation.
The situation could be going out somewhere or with someone one would consider unpleasant, working on something or with someone unpleasant and so on...
This phrase is generally heard in Northern England, commonly in the Newcastle area. One may hear it on Geordie Shore.
Variants:
I'm sick of me life
Am sick of me life
Sick of me life, me
Have got to go to work wi Holly.
Wouldn't want to spend 5mins in a room wi her never mind work.
I'm sick of my life
Precedes or follows either a gratuitously disrespectful or honest remark, originated in New York City. Used in similar fashion to "no offense" or "to be honest," interchangeably.
Ya mans is wild buns, respectfully. Respectfully he's washed.
After school, The Modells on Jamaica Ave was active. Respectfully.
Adjective. Used to describe persons who have adjusted or altered their lifestyle for environmental reasons. Crunchy persons tend to be politically strongly left-leaning and may be additionally but not exclusively categorized as vegetarians, vegans, eco-tarians, conservationists, environmentalists, neo-hippies, tree huggers, nature enthusiasts, etc.
Also used to describe establishments where alternative foods and products are sold, i.e. natural food stores.
In a tabletop game, a murderhobo is a player who murders NPCs indiscriminately. This is normally derogatory, referring to a player who totally ignores quests, dialog, backstory, trade, world building etc.
The term is most common with Dungeons and Dragons, but it can be applied to most RPGs where the player is allowed to kill most quest-giving NPCs and NPC traders. E.g. Elder Scrolls, Fallout, Divinity original sin.
DM: The sad little orphan girl tugs at Steve's trenchcoat to get his attention, and ask for help saving her pet dog from...
Steve: I'd like to roll a strength check against strangling the orphan.
Dave: I call dibs on the dog.
DM: You murderhobos disgust me.