sheezie Share definition Flag Ebonics for "sure". Belongs to a group of words that follow the phonetic pattern "eezie". Commonly used as part of the phrase "for sure". E.g. "Saturday is off the heezie for sheezie. You can find me up in one tweezie" (Welcome to Atlanta). sheezie by methical May 13, 2006 Get the sheezie mug.