The most awesomest person ever that comes up clutch when the pressure's on.
Person 1:Hey, look at that kid! He's so cool!
Person 2: Yeah, he's a regular santonio!!
by BlackandGold123456 May 26, 2009
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The MVP of the 2009 NFL Super Bowl.

Wide Receiver for the Pittsburgh Steelers out of Ohio State University.

Made the game winning catch with less then a minute left in the game to put the Steelers in the lead 27-23.
That catch by Santonio Holmes was so amazing, no wonder he won the MVP!
by Peter Ol February 2, 2009
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To make an incredible save or bail out, like Santonio Holmes did in Super Bowl XLIII.
"Dude, we were so almost busted last night."
"Really? How did you get out?"
"Ah, Grant pulled a Santonio Holmes."
"Nice!"
by superbowlxliii February 4, 2009
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A light skin person with the name Santonio Miller is strong, cute always comes in cluch also known has a stoner but is also a Fuxkboy
That person getting my nerves I’m go Slam them like Santonio Miller
by Fuxkboycentral November 7, 2019
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Santonio turner.. the best friend in the whole wide world that's got you're back no matter what !he's great in every which way and is a beast in sports!! Hes always there for you no matter what and when you need all you need to do is ask after all he is the best broski in the world.
Dang look at Santonio turner go again! # 59 scored another touchdown and he cured his best friends heart right before the game!
by Curly fries. August 16, 2017
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