Santonio

The most awesomest person ever that comes up clutch when the pressure's on.
Person 1:Hey, look at that kid! He's so cool!
Person 2: Yeah, he's a regular santonio!!
by BlackandGold123456 May 25, 2009
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Santonio

That Nigga perriodtttt
by anonymous November 23, 2021
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Santonio Holmes

The MVP of the 2009 NFL Super Bowl.

Wide Receiver for the Pittsburgh Steelers out of Ohio State University.

Made the game winning catch with less then a minute left in the game to put the Steelers in the lead 27-23.
That catch by Santonio Holmes was so amazing, no wonder he won the MVP!
by Peter Ol February 01, 2009
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Santonio Holmes

To make an incredible save or bail out, like Santonio Holmes did in Super Bowl XLIII.
"Dude, we were so almost busted last night."
"Really? How did you get out?"
"Ah, Grant pulled a Santonio Holmes."
"Nice!"
by superbowlxliii February 04, 2009
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santonio miller

A light skin person with the name Santonio Miller is strong, cute always comes in cluch also known has a stoner but is also a Fuxkboy
That person getting my nerves I’m go Slam them like Santonio Miller
by Fuxkboycentral November 07, 2019
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Santonio

Santonio is a good looking person /has a awesome personality

He’s very funny makes everyone laugh

He’s cool /popular

He’s a leader

When your mad he makes you laugh
Everyone needs a santonio in there life
by Americanguy4322 March 22, 2025
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Santonio Tucker Jr

A fine ass dark skin with dreads and sexy ass voice
OMG is that, that fine ass dark skin santonio tucker jr
by everybody babymamas October 24, 2022
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