An offshoot of the classic nursery rhyme "Hickory Dickory Dock". Normally used in frustration/anger/disappointment to express one's strong disapproval for the actions and/or nature of a jackass/nigger/over-all douche.
niggered up (adjective); nigger it up (verb) ; a condition in which something that would normally look just fine now looks not so nice usually because of unnecessary additions or messiness
Mom: Our house looked beautiful until Anthony got it all niggered up with all of his cords and shit.