Something that is so disagreeable with your
spirit that it feels like its
existence might negate yours.
This goes further than "hate," and implies that you and the object in question are sworn enemies.
Can be used
seriously or, more likely, exaggerated for comedic effect.
Wearing socks with sandals is the bane of my existence.
The
iPhone's
autocorrect is the bane of my existence.
Stephanie's hair is the bane of my existence.