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-a combination of the words "mother" and "fucker" or more appropriately "motha" and "fucka". A word that can be used on any occassion, sometimes used to start off a long line of partial jibbirish.
"mofuka piece shit scadaba ricky j mocatipi mocananon"
"sup mofucka"
"MOFUCKA!!!"
"best mofukan band ever"
"mofucka.....those are some big mofukan cannons"
mofucka by brianmofuka November 30, 2004
Related Words
When cursing is unacceptable because you're either at church or at a business meeting or among mixed company or you want your underage kids to use a curse word and the verb or noun mother fucker needs to be used you can you mofackle instead.
Confession to Priest: Forgive me father, for i have been a bad mofackle!

In anger: You are on dumb mofackle!

Son: Daddy that mother fucker almost hit us running that red light!

Dad: I know son but please use mofackle instead!
Motherfucker, a person that sucks at life, steals from friends. fucks your sister and mother while wearing your slippers and drinking your purple stuff.
Your brothers a Mofaka for stealin my bread. i got kids'n shit ya scary bitch.
Mofaka by Dirk Dirkenson February 15, 2008
Mafacka

1. Slang for an already slang word; Motherfucker

2. Alternative to Mofo

3. Alternative to Muhfuh
"Man, you seen that guy Jake? He's a real mafacka!"
"Yeah. That mafacka got up in my mafackin' house, and stole all my mafackin' shit!"
Mafacka by Ryan P. M. May 24, 2006

mofacker 

mother fucker, in a polite and lazy manner
You stupid mofacker!!
mofacker by Ram-Dawg April 15, 2003
Term used in the place of mofucker when using it in a more friendly matter, as opposed to an insult.
"Me and that Mofacky are gonna go to Circle K."
Mofacky by Pajewjew January 15, 2006