Madcow 

A diesese which is carried through the air and turns cattles brain to the same mush your grandmother eats at her old folks home. Remember the best way to combat the diesese is to wipe front to back at all times.

Young Hick Boy: "I think that ma's sick pa'

Hick Farmer: "I reckon shes got madcow, time to close the border again (spits tobacco)"

Madcow by Schefter January 1, 2005

Madcow 

A mythical beast that is under 5 feet tall. It is said that it frog squats about tree-fiddy for 10 clean reps. Even with this much weight you would not guess it is that strong. You might even think to yourself "does it even lift"?

Dude, I saw that Madcow do 175 off a 10 board!

Madcow by JoeAverageStrength March 31, 2011

Madcow 

an obese unkept female who is generally found in sweatpants, gets jealous over the hottie/honey dip in the room that her man can't take his eyes off of, sometimes resulting in obvious bickering between the couple who leave the area shortly after the incident. Therefore she becomes a "mad cow" also known to be found happening with skinny ugly girls who have no boobs or personality and buck teeth, bug eyes , etc.

Madcow: has look of hate and eating chicken fried steak with mashed potatoes and gravy watching husband every eye movement and says nothing

Husband : can't control himself and incessantly stares while drooling at hotties taute firm ripe ass- leaves with raging hard on.

<mad cow > < Mad > <cow> <Madcow disease>

Honeydip to friend ; look! that Madcow and her man r leaving now

Madcow by Space cowgirl68 March 31, 2013

Madcow 

When a male ejaculates into his hand and proceedes to pentrate ones vagina with with their fist resulting in pregnancy.

"she said she was asexual so I gave her the MadCow and hit the old dusty trail"

Madcow by Cowslapper October 17, 2018

Madcow disease 

A disease suffered by a fat chick who are so diguested with herself she cockblocks any guy from talking to her attractive friend(s). Fat women who suffer this disease for long periods of time will develop a permanent pissed off demeanor look on their face. They possess chubby perma-frown cheeks resembling a bulldog's jowls.

I was trying to mack on this hot chick and this fat bitch with madcow disease came over and shit all over my game.

Madcow disease by Patrick_B June 17, 2008

Madcow Skills 

To be insanely talented at doing something.

I have Madcow Skills at quarters

Madcow Skills by PookeyBear April 26, 2005

humpin like madcow 

To engage in sexual intercourse frequently. Usualy in an attemy to impregnate. Refers to the motions made by infected cattle

I havent left the house for 2 days, we've been humpin like madcow

humpin like madcow by Horny old man January 2, 2005