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Stands for: Long-Term Male Sexual Abstinence

A condition, typically considered a severe form of long-term virginity, affecting 0.8% of U.S. males approximately 25 years of age or older. Symptoms usually include a combination of the following: the inability to interact with females, shame, depression, loneliness, shyness, and large abundances of pornography (usually very graphic and strange). Clinical research and testing are currently inconclusive as to why males suffer from LTMSA, however it is theorized that an extreme psychological episode from a males’ childhood may be the cause. Previously LTMSA was a relatively unknown condition in mainstream psychohistory until the film “The 40 Year Old Virgin” premiered that brought this condition to the forefront of mainstream research.

LTMSA is credited being first diagnosed in 1955 by Dr. Steven J. Bishop of Georgetown University.
Long-Term Male Sexual Abstinence (LTMSA) usually results in one of two outcomes:
1. Lonely night alone and a bad hand cramp in the morning or
2. Your friends sending out a "Code Orange" alert when there is a possibility for the male in question to lose their virginity.
LTMSA by Super Steve Bishop January 20, 2008
Related Words
Laughing 'Til My Sides Hurt.
Person 1: *Randomly says something ABSOLUTELY HILARIOUS*
Person 2: HAHAHAHAHAHA LTMSH!!!!
LTMSH by fhk x3 May 23, 2016
An abbreviation meaning Laughing To Myself Quietly
IM user 1: HAHA I can tell funneh jokes!

IM user 2: LTMQ i kno!
ltmq by GuitarPlaya December 23, 2005
Laughing to Myself Quietly

For use in texting and the like when you are not actually laughing out loud or laughing your ass off. Props to Demetri Martin for pioneering the phrase.
Harold tells a story that is funny but not that funny via AIM.

Louis replies "ltmq"
ltmq by What a Becoming Shirt June 16, 2010

Long-Term Male Sexual Abstinence (LTMSA) 

A condition, typically considered a severe form of long-term virginity, affecting 0.8% of U.S. males approximately 25 years of age or older. Symptoms usually include a combination of the following: the inability to interact with females, shame, depression, loneliness, shyness, and large abundances of pornography (usually very graphic and strange). Clinical research and testing are currently inconclusive as to why males suffer from LTMSA, however it is theorized that an extreme psychological episode from a males’ childhood may be the cause. Previously LTMSA was a relatively unknown condition in mainstream psychohistory until the film “The 40 Year Old Virgin” premiered that brought this condition to the forefront of mainstream research.

LTMSA is credited being first diagnosed in 1955 by Dr. Steven J. Bishop of Georgetown University.
Long-Term Male Sexual Abstinence (LTMSA) usually results in one of two outcomes:
1. Lonely night alone and a bad hand cramp in the morning or
2. Your friends sending out a "Code Orange" alert when there is a possibility for the male in question to lose their virginity.
Laughing To Myself Silently. Because who is really "laughing out loud" when they type LOL?
You: i fell into a bush earlier

Me: ltms
LTMS by mmmm3 April 26, 2009
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Pee Calculus

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Brent: he just tossed me a slop grenade
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