A rare hereditary condition that unfortunately has no cure. It affects the ability of the sufferer to move around quickly and wear tighty whities. It is also known to instigate "peeking" among other males while using public urinals. Consequently if you are infected with Longdongtinitus, most of your sexual partners might need to be taken to the emergency room after penetration.
Dirk - "Just got back from the Pediatric Gynecologist today and I have some bad news, I've been diagnosed with Longdongtinitus"
Dumb Slut - "Oh nooooo, what are you going to do?"
Dirk - "Just drink this ruffie colada and I'll show you"
While our lifespan is the number of years we will live, our healthspan is the number of healthy years we will have and our sexspan is is the number of years we will continue to be healthy enough to continue having an active sex life.
A lighthearted reaction upon receiving disappointing news of some sort. Usually something that isn't a particularly a big deal, esp. when it primarily affects someone else - sort of a mild schadenfreude. Sometimes doubled or tripled, and possibly said in a sing-songy voice for added comedic effect to imitate a muted trumpet, which is how the meme originated.