1.A program proposed by Apple, which incorporated sex into the Mac OSX desktop, which was initially accepted and then rejected, after CEO's thought that it might be contrary to Apple's public image.

2. Internet sex via two Macintosh Computers.

3. A computer with a ridiculous amount of porn on it.
Man, I was really looking forward to iSex.

Boy: Hey wanna iSex?
Girl: Wait 'til my parents leave.

Friend: Damn! Your computer is a freaking iSex
by Johnathan Mc Nads April 12, 2006
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An act that occurs when someone is staring at another person so hard that they are fucking them in their head.
I totally don't know if I should feel violated or like having a cigarette, the way that Alison was just isexing me!
by Heyuguy June 27, 2021
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