guacala! Share definition Flag From the Quechua dialect meaning disgusting. Expression used often in the Ecuadorian community. Sometimes spelled as "Wacala!" David was talking about his "man juice" and Pamela's first reaction was "Eww Guacala!" guacala! by BettyHill April 2, 2007 0 0 Get merch Get the guacala! mug. Buy Now — $32.95 See more merch