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z'ed up from the feet up 

derives from being zooted
when you are just so high/drunk after a heavy night of partying
"hey how are you feeling?
man, im z'ed up from the feet up"

Ed Zachary Disease 

Ed Zachary Disease is when your face looks exactly like your ass, meaning you are extremely ugly.
"Ed Zachary Disease is when your face rook Ed Zachary rike your ass." - Dr. Chang of China
Ed Zachary Disease by -Brad- May 24, 2006

Ed Zachary Disease 

When someone's face looks Ed Zachary like their ass.
Once, an ugly girl that was making a pass at me described that she wasn't feeling very well.
I said, "Well, if I were a doctor, I think I might diagnose you with Ed Zachary Disease."
She asked what it was and I said, "When your face look Ed Zachary like yo ass."
She wasn't amused.
Ed Zachary Disease by Roy L'Ourtiere September 7, 2008

Ed Zachery Disease 

Very nasty disease that prevents women from getting dates or having sex. This was coined by Dr. Kayoto, the very well-known Japanese sex therapist.
Your probrem vewy bad, you haf Ed Zachery Disease."
Ed Zachery Disease? What's that?"
"Vewy sad. It's when your face rook Ed Zachery rike your ass."

Also see Butterface, or ButHerFace
Ed Zachery Disease by TimmyH September 8, 2006

M.E.D.Z.A.R.P.T.H. 

An incurable STD that is like a blue waffle times 1000 that causes your genitalia to turn black, seep, farm boils, and eventually fall off. It lives troglos underpants and is both airborne and fatal.
I know may people who have died of M.E.D.Z.A.R.P.T.H.
M.E.D.Z.A.R.P.T.H. by vv.12.12.c| December 7, 2011