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Churchill Downs 

Slang for Ketamine - named because of it's use as an anesthetic on horses

A substance commonly used for Anaesthesia of animals and small children. Popularized by John Lilly as a psychoactive substance somewhat related to Phencycledine (PCP) in effect. In Timothy Leary's 8-circuit-model of consciousness this drug is associated with the 8th and highest circuit. Effects of a solid dose (particularly injected) include intense OOBE's (out of body experiences), Lilliputian hallucinations (feeling "as big as the universe" or "as small as an electron", often simultaneously) and other such psychedelic effects.
"Tonight's gonna be weird; we're going to Churchill Downs!"
Churchill Downs by Irwij October 21, 2009
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Churchhill Down Syndrome 

Closely related to the birth defect Down Syndrome. Which those with the condition have a widely recognized appearance. Churchhill Down Syndrome cause those with the defect to develop horse face. Symptoms vary from person to person and can range from mild to severe. Long face, buggly eyes, and protruding gums and teeth are typical signs of Churchhill Down Syndrome.
Sarah jessica Parker, Celine Dion, and Tori Spelling are examples of celebrities who suffer with Churchhill Down Syndrome.