Breakthrough 

The full transcendence of one's consciousness into another dimension through the medium of certain psychedelic drugs. These psychedelic breakthroughs are achieved mainly through very high doses of DMT, salvia divinorum, amanita muscaria mushrooms, ibogaine, or psilocybin.

After I took three very large inhalations of DMT I experienced a breakthrough into the sacred realm known as Hyperspace.

Breakthrough by Metatronix October 27, 2009

Breakthrough 

During extreme impaction constipation, enemas and oral laxatives must be used. Breakthrough occurs when you finally shit out the last of the acorns and the diarrhea from your oral laxatives finally breaks through the fist sized corm of fecal clumps you were trying to squeeze out of your dry, fissured anus, giving you that sweet relief of liquid diarrhœa. Usually accompanied by uncontrollable vomiting.

To the photo lab technician in Walgreens: Those enemas and laxatives really helped me achieve breakthrough last night.

Breakthrough by marcus daniel malloid March 2, 2023

Breakthrough 

During extreme impaction constipation, enemas and oral laxatives must be used. Breakthrough occurs when you finally shit out the last of the acorns and the diarrhea from your oral laxatives finally breaks through the fist sized corm of fecal clumps you were trying to squeeze out of your dry, fissured anus, giving you that sweet relief of liquid diarrhœa. Usually accompanied by uncontrollable vomiting.

To the photo lab technician in Walgreens: Those enemas and laxatives really helped me achieve breakthrough last night.

Breakthrough by marcus daniel malloid March 2, 2023

Breakthrough Manchester 

A great program held at the Derryfield School in Manchester NH.You apply in fifth grade , spend the next 2 summers there and a few schooldays a month.It has changed my life enourmously.Formerly Summerbridge.

Me-I went to Breakthrough Manchester
Freind-NERD

five years later

Me-I found a cure for cancer
Freind-do ya want fries with that?

Breakthrough Manchester by *StrawberryFieldsForEver* December 18, 2008

blackout breakthrough 

After a good night of binge drinking, in which you blackout, there comes a moment of clarity the next day, where you are finally able to recant on the previous nights shenanigans.

ArJay, "Damn Jimmy I was soo hammered last night I just remembered that Bobby got Iced by a fifty year old lady!"

Jimmy, "I totally forgot about that one too. Great blackout breakthrough"

blackout breakthrough by ArJizzld August 18, 2010

Amazing Breakthrough 

An instance of involuntary defecation that is so severe or powerful that it soaks though one's trousers.

After eating a roast beef sandwich at a popular fast-food restaurant that shall remain nameless, I became so ill I had an Amazing Breakthrough!

Amazing Breakthrough by Dr. Papuj December 26, 2012

Vibration breakthrough 

When your almost for certain that you’ve found the frequency you have been searching for, to the point you stand off set take things slow and analyze the very story to unfold, although when you feel vibrational breakthrough. Your almost 100 % certain your going to give your partner in the vibe the most wildest sensation of sexual intamicy they have ever experienced to the point they crave your very taste and smell you and get horny and any random acasion afterwards.

Man she’s so incredible she makes my genitalia throb with vibration breakthrough

Vibration breakthrough by Titus dyfilid February 13, 2019