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autoimmune 

The immune system is a complex organization within the body that is designed normally to "seek and destroy" invaders of the body, including infectious agents. Patients with autoimmune diseases frequently have unusual antibodies circulating in their blood that target their own body tissues.
the infection triggers an autoimmune response
autoimmune by stoneygeek July 10, 2017
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Autoimmune disease 

Pretty much pressing the “self destruct button” on your body
Me: *gets diagnosed with an autoimmune disease*

Body: I’m going to fuck you over
Me: for how long?
Body: forever.
Autoimmune disease by Peanuts b December 11, 2018

autoimmune disease 

A disease in which the body produces antibodies that attack its own tissues, leading to the deterioration and in some cases to the destruction of such tissue. In simpler terms, it is when your immune system...is...bad.
Ayesha had to start taking medication when she got rheumatoid arthritis, a type of autoimmune disease.
autoimmune disease by Ex-Quitter August 4, 2009

Autoimmune disorder 

The condition many people are born with that makes their life a never ending vortex of pain and suffering so pretty much hell
Man autoimmune disorders suck

Autoimmune Hepatitis

A rare disease of the liver, which may cause the spleen to expand and rupture. Someone with this disease is a must-have at every party.
Hey, man! Did you see that guy with autoimmune hepatitis? His spleen's fatter than yo momma! We should invite him to the next party, so we can look good when compared to him!
Autoimmune Hepatitis by Chrissy_B November 22, 2011

Auto immune 

Someone who tragically does not understand the appeal of sexy, fast cars.
I love the new BMW convertible but my husband is Auto Immune and drives a boring SUV.
Auto immune by Faster Redhead December 15, 2021

auto-immune disorder 

An serious illness characterized by the inability to resist the allure of motor vehicles, whether it's buying more cars than you need, needlessly driving/riding in them for extended periods of time, tinkering/upgrading them unnecessarily, etc.
Tim The Tool-man couldn't resist driving his wife's antique Austin-Healey sports car even though she'd expressly forbidden him to touch it. He admits that he has auto-immune disorder --- he's thinking of checking into the Henry Ford Clinic. :P
auto-immune disorder by QuacksO July 19, 2018
More from Urban Dictionary

You met me at a very Chinese time in my life

A moment in time where you feel distinctly Chinese over all other things.
Dante: "I wish I could be Nigerian, but I can't because I'm Chinese. You met me at a very Chinese time in my life."
Word of the Day on September 25, 2026
Adjective. Used to describe persons who have adjusted or altered their lifestyle for environmental reasons. Crunchy persons tend to be politically strongly left-leaning and may be additionally but not exclusively categorized as vegetarians, vegans, eco-tarians, conservationists, environmentalists, neo-hippies, tree huggers, nature enthusiasts, etc.

Also used to describe establishments where alternative foods and products are sold, i.e. natural food stores.

Modified derivative of granola.
"I need more crunchy guys in my life. I'm so tired of dating preppy metrosexual assholes."

"I'm heading out to the crunchy store to pick up some fair trade chocolate and tea tree oil, do you need anything?"
crunchy by EBC July 11, 2007
Word of the Day on September 24, 2026
A group of people, typically women, searching through someone’s digital footprint in order to find more information about that person.
Susie wasn’t sure if her new Hinge match was a creep, so she assembled Galantir and they found out he used to post slurs on gaming forums.
Galantir by Ge-sus September 22, 2026
Word of the Day on September 23, 2026

murderhobo 

In a tabletop game, a murderhobo is a player who murders NPCs indiscriminately. This is normally derogatory, referring to a player who totally ignores quests, dialog, backstory, trade, world building etc.

The term is most common with Dungeons and Dragons, but it can be applied to most RPGs where the player is allowed to kill most quest-giving NPCs and NPC traders. E.g. Elder Scrolls, Fallout, Divinity original sin.
DM: The sad little orphan girl tugs at Steve's trenchcoat to get his attention, and ask for help saving her pet dog from...
Steve: I'd like to roll a strength check against strangling the orphan.
Dave: I call dibs on the dog.
DM: You murderhobos disgust me.
murderhobo by Loup&S September 9, 2021
Word of the Day on September 22, 2026
In sales terms, a whale is a prospect that is significantly larger than an organization’s average customer.

Whales are large and extremely difficult to close. Due to their immense size, they are highly sought-after.

A whale is typically identified at first by a whale hunter on the sales team, but often requires cross-discipline participation in order to close; this includes assistance from operations, engineering, creative, client success, and business development teams.
"Shit...the sales director chewed me out on the sales call this morning. He's totally pissed that I have nothing in my pipeline. I've been focused on this one whale for so long that I haven't had time to prospect for normal-sized deals."
Whale by FQ_GFY February 3, 2020
Word of the Day on September 21, 2026

Concrete cowboy 

A guy who thinks he's a country kinda guy, but in reality lives a comfortable city / suburban life.
Eugene: Look at that dude in the cowboy hat!
Todd: He's just a concrete cowboy.
Word of the Day on September 20, 2026
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