Said after someone tells or asks you to do something that you're too lazy or you just don't want to do. Can be used the same as "fuck that" or "I don't want to" .
Used to provide reasoning for seemingly random, unexplainable events that occur that result in unfortunate outcomes. Most often used for video gameRNG.
Guy 1: Damn, why'd the teacher give decide to give us a pop quiz today? I didn't study!
Guy 2: Because screw you, that's why!
When you have to pee in a movie but don’t want to miss anything, and must do the following mental equation: will the amount I have to pee cause enough discomfort to diminish my attention capacity for the remainder of the movie to an extent which is greater than the amount of the movie I would miss by making a mad dash to the restroom.
I saw Satantango last night, wonderful film but by the 5th hour I had to start doing pee calculus.
Short-hand for the word floccinaucinihilipilification, meaning the estimation of something as valueless (encountered mainly as an example of one of the longest words in the English language).