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Silly Syndrome 

Silly Syndrome is the incapability to be serious. Symptoms may include making silly faces, constantly trying to make people laugh, peculiar vocabulary, and being bat shit crazy in any situation.
"Did that guy just say goopy and grunky in the same sentence?". "Yeah he must have Silly Syndrome"
Silly Syndrome by Ascher May 2, 2023

Silly Nigga Syndrome 

To have no grasp on reality. To have no logic whatsoever. Incapable of looking further ahead of about a minute and a half in the future.
The judge awareded him his disability based on the doctors diagnosis of his irroversable silly nigga syndrome.
Silly Nigga Syndrome by Skip Bonds January 15, 2020

SBS (Salty Ball Syndrome) 

When you go swimming in the ocean with only a bathing suit on. Then the ocean water evaporates leaving your balls laden with salt. The friction generated when the salty ball(s) rub against your leg causes painful burning afterwards.
Guy 1: Dude why aren't you keeping with the pack we have only been walking on the beach for 2 minutes.

Guy 2: I went swimming earlier in the ocean and now I got vicious SBS (Salty Ball Syndrome).

Guy 3: Duuudddeee.

silly man syndrome 

silly man syndrome often referred to as SMS, (sometimes mistaken for messages) is a serious mental illness which can occur in individuals aged from 3 years old to 15. common symptoms include impaired brain functions, not understanding words said by others and forgetting basic knowledge of different subjects like writing or reading. PLEASE MEET WITH YOUR GP OR MENTAL ADVISIOR IF ANY SYMPTOMS OCCUR. this be permanent if not treated immediately.
oh no, you have been diagnosed with silly man syndrome.

salty nigga syndrome

When a guy talks shit about a girl he used to date/like that doesn’t want him.
Gina: Hey Ruth, I heard Luke was talking shit about you.

Ruth: Whatever. He just has salty nigga syndrome.

Silly Goose syndrome

“Oh,Todd’s dad just died and he was diagnosed with silly goose syndrome. That’s why he hasn’t been in school”