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Pilot slang. Being unable to take one's eyes off a target(enemy aircraft, escort package or some fine lady in a bar) for fear one will not be able to find it again.
Billy : ''Hey Johny, come and watch the game with us over here''
Johny: ''No way dude, I padlocked Ginger''

Gordon: ''Padlocked bogey, requesting protocol CHICANE''
padlocked by goldenb0y February 23, 2008
A piece of software designed to prevent advertisements from appearing on a Web page
I have installed an adblocker on my computer .
Adblocker by Rabbit Shakespeare September 21, 2016

Padlocked Hipster 

When someone with a padlock walks up to a unsuspecting hipster with large tunnel plugs and locks it into their ear, and runs like fuck
We should go do a Padlocked hipster
Padlocked Hipster by M/L/E March 6, 2011

Turn off your adblocker

An extremely idiotic thing websites use, basically it's like waving a cross (adblock) at a demon (person with adblock) to go away or turn it off.

Once you turn it off, they log all your personal information and say thanks.
You: I am thirsty for info, let's go to this news website.
*You scroll down slowly, reading each line*
Website: Turn off your adblocker to keep viewing this website
You: Go away
*Closes website*
Turn off your adblocker by Trumpium December 15, 2021
Cockblocking on a more extreme and personal level.
David likes marks sister. david plans too make an advance on his sister when mark tells him that dave his best friend. In this way Mark has cockblocked dave on a more extreme personal level. (padlocked)
Padlocked by the padlocked boy June 12, 2010
A browser extension/app/addon/plugin which blocks advertisements/ads/adverts
This is something you should love, but not too much (as it decreases revenue to the advertiser).
Some adblockers, mainly ABP and Adblock, even the Chrome Built-in Adblocker enroll in the Acceptable Ads program.
This allows some good ads, but blocks shitty ads. However, this can be disabled (except for chrome built-in).
Hornorable mention: uBlock Origin
Some scummy websites may ask you to "disable" your adblocker, but theres an app for that with fuck overlays (or nope to overlays), scrollfucker, and sometimes the userscript aak (anti adblock killer)
A: Man i fucking hate ads
God: go to adblockplus.org
A: Oh wow thank you god for giving me the adblocker i can now browse peacefully
Adblocker by Preinstallable June 4, 2020