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got a hand on my brain

hippies and stoners in referring to the physical sensation of being "stoned" or high on really high potency thc
Man that is really good. I "got a hand on my brain."

altered my brain chemistry

movie, song, a piece of art or something else that changed you drastically, made you basically a new person or heavily influenced the way you perceive world around you, other people etc.
This song altered my brain chemistry, I basically became someone else after listening to it!

wrap my brain around it 

"That algebra equation is really difficult. I can't wrap my brain around it"

Wrinkling my brain 

A phrase that comes from Troy on Community. It basically means "blew my mind", or a "glass shattering moment".
Annie: Did you know that someone who has already been born could live for 800+ years?

Troy: That's wrinkling my brain!
Wrinkling my brain by Eolus October 18, 2011

My brain just lagged

The word you say when you see or hear something so confusing that you spend a literal 10 seconds to process what just happened.
Friend: But why where we need this that or something fool consequences?
Me: Oh wow, my brain just lagged.
My brain just lagged by The7Guy November 12, 2020

Tattooed on my brain

A memory that one has that one can never forget and every so often it comes around and you have to deal with it.
Man1:I saw my grandmas pie and I can't get it out of my mind it's tattooed on my brain.
Man2: It's your memory so don't give it to me.
Man1:I wish the brain had an erase botton.