Muthabitch Share definition Flag 1. One who resembles a banana in the face. 2. One who is despised by many people. Look! That girl is a muthabitch! Whoa! Shirley, did you say that Kelli is a muthabitch? Muthabitch by Brian Henry November 10, 2005 0 0 Get merch Get the Muthabitch mug. Buy Now — $32.95 See more merch