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knob rot 

The disease responsible for any man needing to become circumcised in adulthood instead of as a baby. Other medical reasons will be cited, but those are obviously all lies employed to cover the embarrassing truth.

Knob rot can be avoided by careful daily cleansing and keeping things safe during sex.
First guy: I was circumcised at 22 because my foreskin wouldn't retract properly.
Second guy: A likely story. Admit it - you had knob rot!
Third guy: Three words, dude - soap. And. Water. Keep it clean next time!
knob rot by Jennan_the_Mad February 8, 2008

knob rot 

A disease men catch when they cheat on their girlfriend/wife. Will end in the knob falling off.
“Hey wow look at him”
“nah id keep away hes suffering from a bad case of knob rot”
knob rot by Kristie_and_Natty August 31, 2006

Knob Rot 

wen sum1 is a nob rot, they usually hav a rotten nob, and its an offensive word
oi u, u nob rot, gimme a fag u dirty litle ratboy
Knob Rot by dan January 10, 2004

galloping knob rot 

An amusing slang term for any of a number of venereal diseases. While the word is most commonly used in reference to gonorrhea and chlamydia, it can describe any STD other than HIV/AIDS. Also known as knob rot and crotch rot. Extreme cases may be classified as Rampant Galloping Cock Rot.
What the fuck? I bang a couple of hoes, and now I've got the galloping knob rot!

Rotch Knob 

When your dick stinks so bad after banging a chick with a absolute rotten crotch.
I wouldn't call that escort service braaaaaaahhhh. The last three hook ups I've had left me with rotch knob. It took days to wash it away.
Rotch Knob by Eaton Holgoode March 8, 2017
Pete was nullified because he got the Knobrot.
knobrot by CabbageClock August 24, 2003