When someone thinks anything mainstream or popular sucks, regardless of the quality.
Dude, you hate The Beatles? Jesus, that's one bad case of Indie Syndrome.
by Steven Spielburg February 23, 2008
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When a girl has a huge pair of tits or ass to the point of either/both of them being disproportionate to the rest of their body.
Man, Sally's got mean Indy Syndrome
by muddafakka January 28, 2016
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A medical condition that plagues men between the ages of 15 and 30, usually recreational writers, artists, or musicians. A person suffering from IBS is characterized as someone who, when alone with a female, constantly says vague and noncommittal things or lapse into silence, waiting for her to respond with something poetic, in hopes that she will fulfill the role of their indie dream girl and like all the same bands as him.
Friend: Did you go out with Jake yesterday?
Girl: Yes
Friend: Well, how'd it go?
Girl: I don't know, we just sort of drove around. Every now and again he'd say something cryptic and like ... wait for me to respond. Total case of Indie Boy Syndrome
by Verevolwes April 24, 2014
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When a girl has an ass or pair of tits disproportionate to the rest of the body
That girl is like 5'3" and has an ass big enough to look huge on someone who's 6'2", talk about Indy Syndrome.
by muddafakka March 14, 2016
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